Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation.
نویسنده
چکیده
Cell-permeable chemical inhibitors have become invaluable reagents for the study of cellular regulation. In the present paper, using protein kinase inhibitors as the example, a set of criteria are described that should be met before any investigation using such compounds should be accepted for publication.
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عنوان ژورنال:
- The Biochemical journal
دوره 425 1 شماره
صفحات -
تاریخ انتشار 2009